General Cell Based Assays
Cayman Chemical a-D-Glucose-1-phosphatesodI 5g
An intermediate in glycogen metabolism; precursor in the biosynthesis of UDP-glucose; can be formed during glycogen breakdown via phosphorolytic cleavage of glycogen by glycogen phosphorylase; can be converted to glucose-6-phosphate by phosphoglucomutase; is combined with CTP to form CDP-glucose in S. typhi
ABclonal Technology HRH2 Rabbit pAb
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Eurofins Discoverx PathHunter Human MC4R(T162I) ENDO-EA Pharmacotrafficking Cell-Based Assay Kit (U2OS)
The PathHunter Human MC4R(T162I) ENDO-EA Pharmacotrafficking Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure pharmacochaperone-based rescue of the mutant MC4R's trafficking to early endosomes. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human OPRL1 (Opioid) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human OPRL1 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure OPRL1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human DRD2S β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human DRD2S β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure DRD2S (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human HCRTR2 Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human HCRTR2 Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure HCRTR2 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human NPBWR2 Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human NPBWR2 Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure NPBWR2 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Abcam Calpain Activity Assay Kit
Calpain Activity Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress BDKRB2 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0189E2CP0L)
The PathHunter BDKRB2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. bradykinin) based activation of BDKRB2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged BDKRB2 and EA-tagged β-Arrestin-2. Activation of BDKRB2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human Total EGFR Detection Kit, 500 Assay Points
HTRF Human Total EGFR Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress EDNRA CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0257E2CP0L)
The PathHunter EDNRA eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. endothelin-1) based activation of EDNRA GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged EDNRA and EA-tagged β-Arrestin-2. Activation of EDNRA stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human & Mouse Total ERK Detection Kit, 96 Assay Points
HTRF Human & Mouse Total ERK Detection Kit, 96 Assay Points
Revvity Health Sciences Inc HTRF 6His Detection Kit, 500 Assay Points
HTRF 6His Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human AQ STING Binding Kit, 10,000 Assay Points
HTRF Human AQ STING Binding Kit, 10,000 Assay Points